Tim Burton is a director that shifted to each medium constantly and stayed relatively aesthetically consistent. The first appearance of his iconic art style is seen in his short film, Vincent. His use of characters with pale skin, big baggy eyes, either monochromatic or flamboyant colors and thin limbs in German expressionist inspired landscapes started in this short film and he would incorporate this into his animation and live action work. A majority of his animated works are done through stop motion, seen with his collaboration with animator Henry Sellick, “Nightmare Before Christmas” and his 2 features “Corpse Bride” and “Frankenweenie” (which was based off a live action short film). For his design work seen in another form of animation, he designed the characters in the Brad Bird directed short film, Family Dog. This design philosophy is prevalent in his aesthetically darker films such as Sleepy Hallow and Sweeny Todd, with main characters with pale skin and all dressed in black. His use of sets also adds to this, for example in Beetlejuice, when the main characters shrink down
Seth Macfarlane is known for creating shows like Family Guy and American Dad. The way the framing of shots is drawn in those shows are similar to multi camera sitcoms so it was easy for him to transition to live action sitcoms with shows like The Winner and Dads, which also evolved into him directing several movies such as the Ted movies (featuring a CGI animated main character). The same can be said for Mike Judge, known for creating the animated shows, Beavis & Butthead and King of the Hill. The characters in his animated shows are known to be created through the observation of the quirks of people he has interacted with, as well as parodies of specific groups, through their exaggerated personalities and more true to life character designs. This led to him directing several comedy films, not just the Beavis and Butthead movie adaptation, but live action films such as Office Space and Idiocracy, which featured similar humor to his animated shows.
Links:
10 Best Animation Directors Who Transitioned to Live-Action (screenrant.com)
When Live-Action Directors Do Animation — The Brilliant Highs and Crushing Lows (collider.com)