Femininity and Masculinity are both sets of qualities, attributes and behaviors based on various factors like gender, sexuality, personality, roles in life, etc. Both Feminine and Masculine ideals and views are vastly different in terms of what is found to be appealing in terms of taste, including art, for either set of attributes. While obviously not 100% the case, both attributes have their own views of creating the art they want to create. Some of the traits of femininity are sensitivity and empathy, while masculinity is more known for being assertive and strong. Some of these traits can be shown off in the art a person of either attribute, especially been evident when going for a more stylized form of art like cartooning or comics.
The manga “Rose of Versailes” by Riyoko Ikeda has a very feminine sense of style with it’s enthesis on softer facial features and a focus on more emotive story telling shown through the paneling.
While the “Sin City” comic goes for a more masculine style through it’s more gritty visuals and more literal and action based storytelling.
Some works can strike a balance in terms of art. The manga “Dorohedoro” by Q Hayashida shows this through having characters have softer facial features, but contrasted with a very rough style of linework.
( source for info: Femininity and Masculinity in Art | LARA (drawpaintsculpt.com) )
( art by Riyoko Ikeda, Frank Miller and Q Hayashida )